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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP4
All Species:
26.36
Human Site:
Y57
Identified Species:
41.43
UniProt:
Q02790
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02790
NP_002005.1
459
51805
Y57
G
D
R
V
F
V
H
Y
T
G
W
L
L
D
G
Chimpanzee
Pan troglodytes
XP_508927
414
47057
G55
A
I
A
T
M
K
V
G
E
V
C
H
I
T
C
Rhesus Macaque
Macaca mulatta
XP_001098079
459
51670
Y57
G
D
R
V
F
V
H
Y
T
G
W
L
L
D
G
Dog
Lupus familis
XP_534923
459
51500
Y57
G
D
R
V
F
V
H
Y
T
G
W
L
L
D
G
Cat
Felis silvestris
Mouse
Mus musculus
P30416
458
51554
Y57
G
D
R
V
F
V
H
Y
T
G
W
L
L
D
G
Rat
Rattus norvegicus
Q9QVC8
458
51432
Y57
G
D
R
V
F
V
H
Y
T
G
W
L
L
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512517
419
46551
W57
Q
G
Q
V
I
K
A
W
D
I
G
V
A
T
M
Chicken
Gallus gallus
NP_001006250
442
50413
G57
Y
T
G
W
L
L
D
G
T
K
F
D
S
S
L
Frog
Xenopus laevis
NP_001084916
447
50310
W56
V
S
V
H
Y
T
G
W
L
T
D
G
T
K
F
Zebra Danio
Brachydanio rerio
NP_958877
449
50474
L56
F
V
H
Y
V
G
T
L
L
D
G
S
Q
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL78
439
48777
G64
E
P
F
E
F
S
L
G
K
G
N
V
I
K
A
Honey Bee
Apis mellifera
XP_395748
459
51510
K63
E
P
F
Q
F
E
L
K
K
G
S
V
I
K
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781282
422
47590
F56
T
T
E
E
D
R
P
F
K
G
D
K
V
F
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141458
458
51432
Y57
G
D
R
V
F
V
H
Y
T
G
W
L
L
D
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38931
551
61434
Y64
G
D
E
V
E
V
H
Y
T
G
T
L
L
D
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.9
98.4
91.7
N.A.
89.7
89.9
N.A.
46.4
74.7
66
61.2
N.A.
41.3
47.7
N.A.
45.9
Protein Similarity:
100
90.1
99.5
97.5
N.A.
95.4
95.2
N.A.
65.3
86
80.6
82.1
N.A.
61
64.4
N.A.
64
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
6.6
6.6
0
0
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
26.6
20
13.3
0
N.A.
26.6
26.6
N.A.
20
Percent
Protein Identity:
N.A.
89.9
N.A.
28.4
N.A.
N.A.
Protein Similarity:
N.A.
95.2
N.A.
45
N.A.
N.A.
P-Site Identity:
N.A.
100
N.A.
80
N.A.
N.A.
P-Site Similarity:
N.A.
100
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
7
0
0
0
0
0
7
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% C
% Asp:
0
47
0
0
7
0
7
0
7
7
14
7
0
47
7
% D
% Glu:
14
0
14
14
7
7
0
0
7
0
0
0
0
0
0
% E
% Phe:
7
0
14
0
54
0
0
7
0
0
7
0
0
14
7
% F
% Gly:
47
7
7
0
0
7
7
20
0
67
14
7
0
0
47
% G
% His:
0
0
7
7
0
0
47
0
0
0
0
7
0
0
0
% H
% Ile:
0
7
0
0
7
0
0
0
0
7
0
0
20
0
0
% I
% Lys:
0
0
0
0
0
14
0
7
20
7
0
7
0
20
0
% K
% Leu:
0
0
0
0
7
7
14
7
14
0
0
47
47
0
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
14
0
0
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
7
7
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
40
0
0
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
0
0
7
0
0
0
0
7
7
7
7
0
% S
% Thr:
7
14
0
7
0
7
7
0
54
7
7
0
7
14
0
% T
% Val:
7
7
7
54
7
47
7
0
0
7
0
20
7
0
7
% V
% Trp:
0
0
0
7
0
0
0
14
0
0
40
0
0
0
0
% W
% Tyr:
7
0
0
7
7
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _